In today's digital-first world, organizations face a constant barrage of sophisticated cyber threats, increasing regulatory scrutiny, and evolving operational complexities. This panel session will examine the imperative for seamless collaboration across the three lines of defense – the business (first line), risk management and compliance (second line), and internal audit (third line). Our expert panelists will discuss how to move beyond a siloed approach to establish a cohesive and dynamic risk management ecosystem. Key topics will include adapting traditional three lines of defense models to the speed and scale of digital transformation, leveraging data and technology for enhanced risk intelligence, fostering a culture of shared responsibility, and ultimately building greater organizational resilience against evolving threats and challenges.